I used to take weekly shots of methotrexate for RA. I didn't know it could harm the kidneys; I just knew it could harm the liver. Anyway, my rheumatologist died and I quit the methotrexate since there was no other rheumatologist in the area (Montana). I was sent to a rheumatologist in Duluth where I now live when my sed rate was found to be very high (normal crp, though). He started me on a low dose of methotrexate tablets and then the COVID came along after a month and I quit the meds since I didn't want to face a pandemic with a suppressed immune system. I don't want to try biologics since they can make one susceptible to lymphoma. What I would like to try is medical cannabis since it apparently has anti-inflammatory effects. After I get a COVID vaccine I may ask for medical cannabis. He could throw me out on my ear, although so far he has been a nice man. Inflammation is dangerous, too. If I could just get my sed rate down I would be happy--the RA is just something I live with and tolerate pretty well. I also have Hashimoto's for what it's worth.