No, I haven't. I will. Thank you. I have had a problem with constipation my whole life. I have taken so many laxatives, drank Miralax, you name it. A couple of weeks ago, I asked my doctor to prescribe Lizness (which I saw on TV). She did and I took one as directed. Take in morning before eating. Later, that night, I was nearly asleep, around midnight. I felt sicker, like I was going to vomit, every nerve in my body was saying something, My bp went up to 200/105 pulse 135. It really scared me, I thought I was going to have a heart attack. I did go to the bathroom, it did it's job but what H I went through. Since the rx cost $65, I paid $65 for one pill. Since then, my bp has been up several times--so, I can't blame the pill, can I?