@sunnyflower I have both Small fiber and Large fiber neuropathy (plus a load of spine issues, but I won't bore you with those ;-)I'm completely numb from my waist down to the bottom of my feet, yet I get really intense pain in both legs, particularly around my knees. My local osteopath ordered x-rays of both knees and both hips, and those showed some osteoarthritis, but not enough to explain the intense pain at my knees. I'm heading up to Mayo in late July for a week of appointments with doctors in Pain Medicine where they will address both my issues with neuropathy and my very arthritic, scoliotic spine. Wish me luck!