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DiscussionTaking Eliquis and Metoprolol for A-fib: Concerned about side effects
Heart Rhythm Conditions | Last Active: May 2 9:48am | Replies (65)Comment receiving replies
Replies to "There are approved and available reversing agents for Eliquis and Xarelto since 2018."
It is important for Connect members to know a lot more about the reversing agent suggested by @darbybauer for serious bleeding when it is related to the anticoagulants Eliquis and Xarelto. The reversing agent is Andexxa, and it was indeed approved by the FDA in 2018. But Andexxa is not a pill to take with lunch. In the FDA news release announcing approval of Andexxa, you may find the following expert statement: "Andexxa's rapid reversal of the anticoagulating effects of rivaroxaban and apixaban will help clinicians treat life-threatening bleeds, where every minute counts."
Note the reference to the use by "clinicians treat(ing) life-threatening bleeds, where every minute counts." The crucial implications of that statement are 1) Andexxa is for intravenous application not an at-home antidote; 2) it is recommended for use by "clinicians" in a highly specialized treatment environment; 3) its use is recommended when a bleed is life-threatening. Be careful and be sure of the presence of a qualified medical professional when an antidote is needed for a bleed while taking Eliquis or Xarelto. Martin
@darbybauer, welcome. I noticed that you wished to post a URL to an article with your message. You will be able to add URLs to your posts in a few days. There is a brief period where new members can't post links. We do this to deter spammers and keep the community safe. Clearly the link you wanted to post are not spam, so allow me to post it here.
– FDA Clears First Reversal Agent for Rivaroxaban, Apixaban Anticoagulants https://www.dicardiology.com/article/fda-clears-first-reversal-agent-rivaroxaban-apixaban-anticoagulants
Darby, have you been prescribed an anticoagulant?