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What do you do for Neuropathy itch?
Skin Health | Last Active: Mar 6 10:24am | Replies (313)Comment receiving replies
@colleenyoung, @lorirenee1, @rwinney, @chandyjohn1, @helennicolla, @stobie2019, @ww2valentine, @johnbishop
I have promised to keep in touch and share information as I stumble through the Neuropathic itch issues. For the last month, I have followed my dermatologist's protocol to include, Sarna cream after the shower which calms the outer skin, Doxepin,10 mg at bedtime helps with staying asleep and not scratching. I still need my medical cannabis to be comfortable during the day and night.
Here is an interesting article about the itch/scratch cycle process especially the neuropathic kind.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502296/
My dermatologist has discovered two medications waiting for FDA approval. The first one, Seriopitant, is explained below.
https://www.dermatologyadvisor.com/home/topics/general-dermatology/serlopitant-benefits-patients-with-treatment-refractory-prurigo-nodularis/
The second one is Aprepitant. I don't see much of a connection with this one but then I am not a health practitioner and just don't understand everything. Here is the Wikipedia explanation.
https://en.wikipedia.org/wiki/Aprepitant
I hope you are all doing well. Colleen, if I left anyone out please let me know. Members, ask more questions and let's see if we can uncover the "witches' brew" for this annoying condition.
And if this sounds repetitive, this is the 3rd time I have written this. It just keeps disappearing.
May you be free of suffering and the causes of suffering.
Chris
Replies to "@colleenyoung, @lorirenee1, @rwinney, @chandyjohn1, @helennicolla, @stobie2019, @ww2valentine, @johnbishop I have promised to keep in touch and..."
Hi Chris @artscaping
Both Aprepitant and Seriopitant are in the same class of drugs called NK-1 receptor antagonists. Currently, the main indication is for nausea and vomiting of chemotherapy.
I asked my neurologist if he knew of any use of these for the pain of peripheral neuropathy, particularly the burning pain associated with minor pressure, like wearing shoes or the touch of bed sheets (called allodynia). No answer yet.
Jeff
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Interesting articles Chris. Thanks. I discussed in a previous post about my wife's use of a sonicare toothbrush for her foot itch which has been a big help to her. Her itch problem has been pretty bad at times, though it has calmed down a bit in the last few months thankfully. But I want to say that she started using a product called Penetrex (the roll-on not the jar of cream) from Amazon several weeks back and she has found that by using it she gets a lot of relief from her itch problem. It also has helped somewhat with the burning in her feet but it seems to be of most benefit with the itch. It is arnica (homeopathic) based, the main issue with it is it's not cheap at $24 per bottle which lasts her about 2 weeks. I am grateful that her itch has calmed down of late. She has enough to deal with with the burning in her feet and her recent sensitivity to changes in barometric pressure which give her debilitating migraines.So seeing the itch subside has been a nice benefit. Best, Hank