I can only speak about my LIVER TX.-2010.. These rejection meds are very powerfull! What I did was I constantly hounded my transplant dr to get me off Cyclpsorine as is it was ruining my kidneys among many skin cancers . Depending on how long your post transplant and how good a match you were I would talk to my transplant team and ask them to start to slowly ween off these meds to a level where you dont reject but your not gonna ruin the rest of your body or get cancer. Right now after 10 yrs Im only on cellcept 500mg-day 250mg-nite. For those of you who take Statins --these meds like cyclosporine interact with statins and cause renal problems.That was another reason they finally bowed their heads and took me off cyclosporine. Remember most Drs only go by PROTOCOL!!