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COVID-19 and Transplant Patients

Transplants | Last Active: Mar 6, 2021 | Replies (459)

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@wildcat

https://www.ncbi.nlm.nih.gov/pubmed/21752960
This is the paper I mentioned which discusses the possibility that cyclosporin inhibits some coronavirus. Please note that it is dated 2011 and, of course, makes no mention of Covid 19. Even then, it applied only to some of the many coronavirus types.There are other papers which suggest that tacrolimus has the same properties. I mention these papers, not to give anyone false hope, but to suggest that our wonderful scientific community will, I'm sure, be looking at all these connections.

Here in Scotland, life has become very different especially for transplant patients. We are to be ' Shielded' - a new term to describe these strict measures- and must not leave home for the next twelve weeks. We must also practice social distancing, as much as possible, from our family members. It is okay but I already seriously miss having a cuddle! i am lucky as my husband is doing all our shopping and taking his 'hygiene' duties very seriously.

My thoughts and prayers are with you all in these difficult times.

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Replies to "https://www.ncbi.nlm.nih.gov/pubmed/21752960 This is the paper I mentioned which discusses the possibility that cyclosporin inhibits some coronavirus...."

Good to know as I was worried about the opposite effect of taking Tacrolimus. Reading into further articles mentioned I get the impression Tacrolimus is twice as strong as Cyclosporin for inhibiting certain viruses. I will bring this up at my Mayo appointment, if it isn't cancelled, and let everyone know.

To you who are commenting about this article, I urge you - Please note that it is dated 2011 and, of course, makes no mention of Covid 19."

Background:
This post is in response to a questionable statement made in another discussion several days ago. The member had heard "that both cyslosporin and tacrolimus have been effective in stopping the replication of some types of coronavirus in the past." Not wanting to start a rumor or spread false information I asked for someone to share where that information originated. I want to thank @wildcat for locating and sharing the information with us in the COVID-19 discussion.

I beg all of you to remember that scientists are constantly researching and exploring medicines and treatments even in the best of times - that is what they do! Please take this article and information for what it is, namely research. Please do not take it out of context.

Let us be careful to not misinterpret the results as they are 9 years old. Instead take it a a sign of hope and give credit to our transplant researchers who are always looking out for our well-being.

@jerrynord, @jolinda, @contentandwell, I hope this makes sense.