← Return to Polymyalgia Rheumatica (PMR), prednisone and Coronavirus COVID-19

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@vernl

Hi Guys,
I have followed this chain for some time but am only now jumping in with a comment.
Three years ago, I too was diagnosed with Polymyalgia Rheumatica. For several months I could hardly roll out of bed in the mornings and then barely walk.
Finally my doctor was able to figure out that I had PR which resulted from a Flu shot. He put me on the steroids and after a couple of months it went away.
Since then, no PR, no problems and definitely no more Flu shots!!!
I had not worried about this issue until now, when I am faced with taking the COVID vaccine. I can't find anything about PR being a side effect, but assume since I was told only a very few folks get PR from a Flu shot, I suspect the PharmLabs didn't even test for this side effect?
I would love to hear from anybody with any thoughts on this subject?
Thanks

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Replies to "Hi Guys, I have followed this chain for some time but am only now jumping in..."

Hello @vernl, I would like to add my welcome to Connect along with @kimh and others. I've had 2 occurrences of PMR but it's currently in remission. I still get my flu shot every year and when available I plan to get the COVID vaccine because I'm at risk by age and health conditions. There is some data about PMR being triggered by the flu vaccine but it's worth the risk for me.

"Immunization has been reported as a rare trigger for vasculitides; a recent review of 1797 adverse events (AEs) reported across three international databases found that PMR represented 9.2% of reported AEs and was more frequently associated with influenza vaccines (3).Dec 16, 2019" - Relapse of polymyalgia rheumatica following adjuvanted influenza vaccine: A case-based review:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002008/
It sounds like your PMR is also in remission. Have you made any lifestyle changes like diet or exercise to help keep the PMR in remission?

Hi, Verni and welcome. A couple of comments: PMR is idiopathic, meaning there is no known cause. There does seem to be some relationship with flu or Shingrix vaccines, and also with stress, but it is hard to know exactly what causes it in individual cases. Also, I’m afraid PMR doesn’t go away. If you have the disease, you will always have it. It’s symptoms can go into remission and usually do with the right dosage of Prednisone or related corticosteroid. If you’re really lucky, the symptoms won’t come back, but that’s the exception, not the rule. In fact the average time from first symptoms to remission without steroids is 5.9 years, so it’s a long haul disease for most. As far as the vaccine is concerned, the flu and Shingrix vaccines include inactivated or partial snippets of the virus they combat. The Pfizer and Moderna COVID vaccines approved thus far do not include any of the coronavirus; rather they are “messenger DNA” vaccines, meaning they are created in a lab to convince our immune system to fight the coronavirus. At least in theory they pose no risk of giving you COVID-19. That appears to be borne out by the tens of thousands in the clinical trials and the early reports from over 2 million vaccinations. In any event, check with your doctor about your situation. Like John said, i view the risk of COVID greater than the risk of side effects (I have PMR and take 10 mg of Prednisone a day after two flares when i thought i was off the drug) so I will be getting the shot when they get to me. I encourage everyone to strongly consider getting the vaccine unleaded their doctor feels otherwise.

That is certainly something to ponder. Can t offer any tips as I am thinking about the repercussions myself ,having temporal arteries . Good luck with your decision.