← Return to Polymyalgia Rheumatica (PMR), prednisone and Coronavirus COVID-19

Discussion
Comment receiving replies
@pfafpa

A few weeks ago, I specifically asked my rheumatologist about Prednisone and PMR. Obviously it is a complicated question because PMR is a disease that results from an overly aggressive immune system. While the trigger is usually unknown, it is known that the adrenal glands produce too much cortisol (often but not always confirmed by blood tests). Prednisone at higher doses shuts down the adrenals, thereby reducing cortisol and “shutting down” the immune system. One of the reason to taper Prednisone is to gradually bring the adrenal glands back to work. At lower doses, probably 20 mg a day or less, (I found one study done in Europe that confirms that) the adrenals are back working (hopefully) so your immune system should be working normally by the time you wean off it. At 10 mg a day or less, you clearly are not at higher risk for Covid-19 by reason of Prednisone ingestion. HOWEVER, everyone is different and many of us have other risk factors, particularly age. So all posts encouraging social distancing and hand washing are right on as we don’t want to find out what a combination of Covid-19 and PMR will be like. (Caveat: i am not a doctor, but rather a lawyer with enough medical knowledge to be dangerous, so discuss with your provider) .

Jump to this post


Replies to "A few weeks ago, I specifically asked my rheumatologist about Prednisone and PMR. Obviously it is..."

Hello @pfafpa, Welcome to Mayo Clinic Connect. Thanks for sharing your experience with PMR. I've had PMR twice but it is currently in remission. I fall into the high risk group due to age and a few different autoimmune conditions so I'm trying to do my due diligence to maintain social distancing, washing my hands and all of the other tips being shared.

Are you currently on prednisone for PMR?

Hi @pfafpa ! I would say you are a lawyer with good instincts. My immune system is a bit wobbly too plus I’m old so I take the advice very seriously. That’s the best we can do!

This post contains the answer I have been looking for since Covid-19 appeared. That at less then 10 mg a day ...are not at higher risk. So thanks for that. I will stick with my 2 g a day now and be able to do my laces up. Of course as you say there are many other risk factors each individual may have, but its one thing less to worry about. I like your comment about being a lawyer. It reminds me of my husband, who was a research chemist, in the way both professions have people who question and delve away at an issue or problem, and never rest until they find their answer. He was a danger to medical staff at times … at least his questioning drove them mad lol.