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Small Fiber Neuropathy turning in to Large Fiber Neuropathy

Neuropathy | Last Active: Apr 8 8:02pm | Replies (42)
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@grandmalele

Yes, an emg can be negative and change in time to positive. I have a fairly recent (6 months) diagnosis of large fiber neuropathy. It didn't show up on a lower body emg 4 years ago when I had a negative MS workup. (Looking, back, I had some mild neuropathy symptoms at least 5 years before that.) The large fiber neuropathy did show up on a current emg which was prescribed because I had developed left-side foot drop. In June my neurology PA prescribed an upper emg because of hand symptoms (numbness, pain, weakness, etc.) It showed moderate severity carpal tunnel in both hands. The testing neurologist noted that the carpal tunnel had neuropathy as an underlying condition and that this was a sign that the neuropathy was starting to affect my hands, even though it didn't show up as a separate finding on the emg (but most likely would in the future.)

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Replies to "Yes, an emg can be negative and change in time to positive. I have a fairly..."
John, Volunteer Mentor | @johnbishop | Sep 4, 2020

Hello @grandmalele, I see that you joined a last month and this is your first post. Welcome to Mayo Clinic Connect. Thank you for sharing your experience. I also have carpal tunnel syndrome in both hands but it's not currently causing me much pain or numbness. I had thought about surgery a few years ago but decided it wasn't that bad yet. There is another discussion you may find helpful.

Carpal Tunnel Syndrome Or Tendonitis?: https://connect.mayoclinic.org/discussion/carpal-tunnel-syndrome-or-tendonitis/

Did your doctor or neurology PA suggest any treatments for the carpal tunnel?

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Rachel, Volunteer Mentor | @rwinney | Sep 4, 2020

Hello @grandmalele! Thank you very much for contributing to this important question. Its important to know and understand what people with neuropathy advancements should look out for. Your experience will help others learn. How awful it sounds to have this continuation of neuropathy. I'm so sorry you are affected in this way. Your hands sound quite painful. Do you find any relief for your neuropathy symptoms?

May today be peaceful for you.
Rachel

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