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Small and Long Fiber Neuropathy – What's the difference?

Posted by Chandy John @chandyjohn1, Feb 15, 2020

What is the difference between Small and Long Fibre Neuropathy?

Interested in more discussions like this? Go to the Neuropathy Support Group.

Mentor
John, Volunteer Mentor | @johnbishop | Feb 15, 2020

@chandyjohn1 -- Excerpt from the link below: "Peripheral nerves contain both large fibers covered with a kind of insulation and very thin, small, uninsulated fibers. The large fibers, for example, carry messages from the brain telling muscles to move. Small fibers transmit sensory information about dangerous stimuli, whether external (pain, burning heat, freezing cold) or internal, and control autonomic (involuntary) functions such as heart rate and blood pressure."

Harvard Medical -- New thinking on peripheral neuropathy (Sept 2019)
-- https://www.health.harvard.edu/diseases-and-conditions/new-thinking-on-peripheral-neuropathy

I see in a previous post you mentioned having diabetic neuropathy. Have you seen the following discussion on Connect?

> Groups > Neuropathy > Diabetic Neuropathy progressing?
-- https://connect.mayoclinic.org/discussion/diabetic-neuropathy-progressing/

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1 reply
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Rachel, Volunteer Mentor | @rwinney | Feb 20, 2020
In reply to @johnbishop "@chandyjohn1 -- Excerpt from the link below: "Peripheral nerves contain both large fibers covered with a..." + (show)
@johnbishop

@chandyjohn1 -- Excerpt from the link below: "Peripheral nerves contain both large fibers covered with a kind of insulation and very thin, small, uninsulated fibers. The large fibers, for example, carry messages from the brain telling muscles to move. Small fibers transmit sensory information about dangerous stimuli, whether external (pain, burning heat, freezing cold) or internal, and control autonomic (involuntary) functions such as heart rate and blood pressure."

Harvard Medical -- New thinking on peripheral neuropathy (Sept 2019)
-- https://www.health.harvard.edu/diseases-and-conditions/new-thinking-on-peripheral-neuropathy

I see in a previous post you mentioned having diabetic neuropathy. Have you seen the following discussion on Connect?

> Groups > Neuropathy > Diabetic Neuropathy progressing?
-- https://connect.mayoclinic.org/discussion/diabetic-neuropathy-progressing/

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Hi @johnbishop. Thanks for posting this info and sheddng light on small and large nerve fibers.

It brings me to wonder if any of our members have begun with Small Fiber which lead to Large Fiber Neuropathy?

I'm going to start a new thread as I haven't heard much about it happening for many.

Rachel

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johnhans | @johnhans | Feb 20, 2020

@rwinney my neurologist told me that if you have large then you have small neuropathy. I was not sure that this is what he said, but was my interpretation of what he said in my brief yearly checkup. I would like to know too if large is just a progression from small or something else.

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1 reply
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Rachel, Volunteer Mentor | @rwinney | Feb 20, 2020
In reply to @johnhans "@rwinney my neurologist told me that if you have large then you have small neuropathy. I..." + (show)
@johnhans

@rwinney my neurologist told me that if you have large then you have small neuropathy. I was not sure that this is what he said, but was my interpretation of what he said in my brief yearly checkup. I would like to know too if large is just a progression from small or something else.

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@johnhans Yes, I agree. It does get confusing which is why we have to stay on top of our game! 😊

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1 reply
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Rachel, Volunteer Mentor | @rwinney | Feb 20, 2020
In reply to @rwinney "@johnhans Yes, I agree. It does get confusing which is why we have to stay on..." + (show)
@rwinney

@johnhans Yes, I agree. It does get confusing which is why we have to stay on top of our game! 😊

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I had saved this Q&A by Dr. Anne Louise Oaklander. Just came across it and thought I'd post for anyone interested in following her research progress on SFPN. She is leading the charge!
http://protomag.com/articles/small-cause-big-pain

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jager5210 | @jager5210 | Feb 20, 2020

This is a related article found on the Oaklander site & may be pertinent for many of us. Problem is finding a doctor(s) willing or capable of this kind of testing...
http://protomag.com/articles/energy-crisis-0

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