I was treated for Stage 1 IDC, has a lumpectomy, radiation and chemo. I have been on Anastrozole for just over 2 years. The 2 worst things that I've dealt with are bladder pain, and joint pain, mainly in my hands. My original oncologist moved right as I finished my treatment, and the practice promised a replacement soon. Well I have seen 3 fill ins..2 were a waste of my time, and 1 was awesome. The last one I saw said he'd never heard of joint pain as a side effect!!!!!! Anyway, I feel a little vulnerable. The pain in my hands sometimes is so bad I can't grip things. My Gyn did tell me about a supplement called D-MANNOSE for the bladder pain. The last time my bladder flared up I got some, and it did seem to help. I also use the AZO max strength, and the spasm seem to go away. My last complaint is being HOT all the time, not really flashes, just hot. I don't want to stop even tho my tumor was small, it came back as a high risk for reoccurance. I don't want to deal with MBC if I don't have to. I have moved to Augusta Ga, so I am going to get a new oncologist.