Yes, I have tried Miralax and Metamucil and Citrucel. Those worked when I was younger (20s & 30s) but when I got into my late 40s those just make matters worse. The Smooth Move tea is now helpful and if that is not enough then I move on to use Healthforce Superfoods Intestinal Movement Formula or Irwin Naturals Daily Gentle Cleanse. I am no doctor and cannot say this would work for everybody but it works for me. I do know that one of the symptoms of Hypothyroidism is constipation and not having enough energy as well as hair loss. I am really feeling like that is the direction I need to concentrate on because without fixing that problem anything else will just be a Band-Aid without getting to the root of the problem. I really do feel I have spent too many years agreeing to the Band-Aid fixes. Would prefer to move forward with my PCP but if I cannot bring them on board to finding the root cause then I will have to work on my own. Hate to say that but I already feel I have lost way to many years.