@webiondev Do you also take tacrolimus? I was initially on both CellCept and tacrolimus then the CellCept was dropped. My creatinine increased from tacrolimus (to the low 140s) so they had me drinking 80 - 100 ounces of water/fluid a day. That didn't bring it down as much as they wanted so they switched me to sirolimus and it has been better since then. I am still making sure I drink at least 60 - 70 ounces of water a day.
How often does your transplant center do lab work? Initially, I had lab work done weekly and then it gradually decreased. I am three years out now and have lab work done bi-monthly. They monitor everything very carefully.
JK