← Return to Positive Dominant Mybpc3 gene carrier, no HCM/ competitive sports?

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Hello @healthgt09,

Welcome to Connect. I’d like to share a few resources that might help shed some more light on your concerns.

MYBPC3 mutations are amongst the most frequent causes of hypertrophic cardiomyopathy. In some studies, MYBPC3 mutants have been associated with a less severe form of HCM with late clinical onset, while other studies have described MYBPC3 mutations to be associated with more severe disease onset, increased LV hypertrophy, and increased frequency of heart failure and sudden cardiac death. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187948

According to The ACC – American College of Cardiology, "Current guidelines recommend restricting competitive sports participation for individuals with HCM to low-static/low-dynamic sports such as golf or bowling,1-3 and vigorous recreational exercise has also been recommended against.4 However, as noted in these statements themselves, there are few data and these recommendations are based predominantly on expert opinion.” https://www.acc.org/latest-in-cardiology/articles/2017/02/20/08/06/sports-and-exercise-in-patients-with-hypertrophic-cardiomyopathy

I'd like to invite into this discussion, a few members who can share their insights: please meet @mommiesboy1 @ccubed @knecht @carjes @margie11 @ronaldpetrovich @vivian88 @jshah and @marlak72
I sincerely encourage you to view these Connect conversations and videos about HCM and genetics:

You may also wish to view this Mayo Clinic webpage, and read some of the younger HCM patient stories:
@healthgt09, I ‘d really like to get to know you better – are you a competitive athlete? Has anyone in your family been diagnosed with HCM?

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Replies to "Hello @healthgt09, Welcome to Connect. I’d like to share a few resources that might help shed..."

All this information is great I am fortunate to find this group. My husband late 30’s is a carrier and has HCM, genetic testing revealed our teenage son is dominant gene positive carrier but he has had ECGs, echos showing healthy heart, no muscle thickness no abnormalities. Very involved in sports so trying to find information or others experiences with decisions they have made with allowing their kids to still play the sports they love if they only carry the gene but are not diagnosed with HCM. I feel that if this is a risk factor information would I be harming his mental health by taking this away from him. Will the doctors consider letting him continue to play sports if he carries but has healthy screenings every year like other kids?