yes.. I went from 27 years of hypo to very bad hyper a year ago. lost 40 lbs. shook bad, don't sleep, and would actually go into a what I call a 'comatose' state for up to 2 hours. I could not drive. it was awful. In my case, I was told I"d have to wait it out ( for the thyroid medicine I was on to get out of my body.). I have my first endo appt in 5 months next week. I have no idea where I'm at right now. 2 months ago, I was still in the hyper lab ranges. BUT.. I am not shaking now anymore, and my wt has stabilized. I still don't sleep though..... I will keep watching this message board. ( I am 55).