@fdixon63 Hi there. I had pseudomonas back in 2016. I was treated with 28 days on inhaled tobramycin. My symptoms disappeared after the 28 days, but I remain to this day on a bi-monthly regimen of tobramycin and ciprofloxacin. I have tested negative for the last three yrs. and my dr says that I will need to be on maintenance antibiotics for life most likely. So far, I have had no side affects from the meds. The reason for lifetime of antibiotics is because of the bronchiectasis. I will always be susceptible to mac and pseudo. So far, my treatment plan has been working. I don't think our goal can be to permanently eradicate these diseases, but rather to prevent them from re-occurring.