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Effexor and Mirtazapine

Depression & Anxiety | Last Active: Mar 30, 2023 | Replies (26)

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@caf

Did the mirtazapine work right away? I’m on my first night , been on 150 Effexor for three weeks, no appetite and trouble sleeping thanks for your feedback!

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Replies to "Did the mirtazapine work right away? I’m on my first night , been on 150 Effexor..."

The Mirtazapine worked very quickly for me. It’s affinity for histamine receptors causes sedation. And it helped me tremendously getting to sleep. Effexor works on norepinephrine, which can cause a feeling of “jumpiness.” That’s why I only start ONE MED AT A TIME. Give the Mirtazapine more time. I did poorly on Effexor. Good luck.