@doorman: Mirtazapine is very effective in calming anxiety. But Effexor (Venlafaxine) does not suit everyone, so one has to be careful with it. It did not suit me and I suffered a terrible withdrawal reaction when I stopped it after taking it for just three weeks. At what dosage are you taking it? How is your body reacting to it? Please indicate the dosages of both meds. Also, are you taking any benzodiazepines or other anti-anxiety meds for immediate relief?