You know what...I literally have unopened low dose naltrexone sitting in my cabinet. Amazing that you sent me this link and thank you very much for doing so. Before being diagnosed with SFPN I spent 2 years with pain management targeting neck and head pain with nerve blocks and radio frequency ablations. After receiving less relief from such procedures and expressing concern over hydrocodone use, PM Dr recommended neltrexone. She had patients get relief from it but advised I could not take hydro, would be counter productive. I ordered it then chickened out to start it because I was not willing to give up instant pain relief from hydro. My PCP prescribed my hydro and is fine with doing it but knows my long term fears of its use. I'm very perplexed, to be honest, in knowing what direction to go in next.