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About ready to scream, been bad month

Lung Cancer | Last Active: Sep 12, 2020 | Replies (54)

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@reibur1951

Update Synopsis as Not sure what posted this summer… friends neck lymph node started growing in Jan. by March really bothering him tried a clinical study of chemo for a few weeks but was still growing by late April when decided to do radiation & genomic testing 10 radiation treatments in May and nothing came of the genomic testing for markers what ever was off the Keytruda during radiation and then went back on it Oct 2nd CT scans brought bad news on the 7th that the lymph node in armpit started growing and one in the chest area these were original old ones – the neck lymph node remained same as the July Ct scans and under control the main tumor has not changed thus far since the end of the 1st clinical study in April 2018 when he began the Keytruda only all other lymph nodes remain stable and unchanged… on the 7th the Keytruda could not be given because of the CT results was told a harsh treatment & possibly keytruda too or that a clinical study was available ( Ant-IDO-1 Agent maybe combined with Anti-PDL-1) it’s a Pahse 1a/1b and last resort would be radiation… Chose the clinical study Eli Lilly it is 10 weeks with on Thursdays and then there are 3 times we have to go back on Friday for blood testing ekg and the 3rd Friday a biopsy... signed papers on the 7th today (18th) we went back for the labs tests, biopsy and ct scan of the abdomen and pelvis ... .

Thursday 24th we start in oral dosing with infusion, 8 hour post blood draw and go back of Friday 25th for blood draw oral dosing and ekg then next to weeks only the labs and oral .....

Been while since posted... summer went way to fast... been cleaning up 5.3 acres a long .ways to go... things finally settled the daughter & husband got her 5A but had to get a variance so could keep farm land frontage nothing ever has been simple bu t went through without question... sale of 40A cent through on Sep 11 and went got new vehicle 2019 GMC Sierra 1500 Elevation series a 4by4 did not have it but 4 days someone keyed/scratched the drivers side from drivers door to taillight .had to totally repaint that side... thus can not be Ziebarted till late December. its paid for in full going to stick it out here another winter if can and put money into restoring my house... me i am hanging in sometimes by a thread i think turned another year older on Sunday trucker friend came in helped us get dyer out of garage/barn not attached to trailer into laundry/furnace room so will provide extra heat when ran and another problem solved that's been on going for 3 years but his family would not help solve... God will provide and guide

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UPDATE into and ending 2nd month of the clinical study - seems to have of side effects - yesterday was our last "long day" they were the Oct 24th, Nov 7th, & Nov 21st Labs/ekg upon arrival, 2 hr, 4 hr and 8 hr, after Infusion/Oral dosing. The Fridays 24, 8, & 22 were labs/Ekg/vitals with labs/vitals only -

The Fridays were basically walk-in and walk-out not even a half hour - more time on the road...

There is 5 trips in dec - 3 of the oral dosing & infusion; one trip for labs only & other will be for CT Scan which she messed with the radiation follow-up appointment from the May radiation treatment with christmas week off then in January will be down to every 2 weeks -

This is the Clinical study: https://clinicaltrials.gov/ct2/show/record/NCT03343613

Participants must not have previously received an indoleamine- 2,3-dioxygenase (IDO) inhibitor

STUDY PURPOSE: The purpose of this study is to evaluate the safety of the study drug LY3381916 administered alone or in combination with anti-programmed cell death ligand 1 (PD-L1) checkpoint antibody (LY3300054).

TIME COMMITMENT: Your participation in this trial could last up to 24 months, depending on your cancer type and how you and your tumor respond.

Hopefully this will help - guess the CT on Dec 18th will tell.

Weather has co-operated - no snow on the days we have gone down - misted rain last night when we came home - got out at 8 p.m. and got home after 10 and turned around and went back at 7 a.m. this morning - we could of had hotel but with wood stove only heat and the animals its not been bad.