.. i think different things work differently because could be different 'reason' for dry eyes and some conditions like my daughters on computers, a quick few drops through the day... but long term and tears not being produced or evaporating too quickly... i had an appointment with dept. head dealing with dry eyes at on of Toronto's teaching hospitals the year i was diagnozed down there with glaucoma, but got cdiff and had to cancel and not been able to travel since, well can manage the 4 hour drive its the fecal incontinence etc. etc. etc. etc. and finding a room during covid ...but honestly i would suggest to anyone starting the dry eye route to see someone who deals with it , reputable and not just selling a fix, and find out 'WHY' and take it from there, i have used and spent hundred and hundreds on eye drops that may not have even been suitable but i must admit have never tried prescription dry eye drops... maybe thats been my mistake. if i sound grumpy its been a couple of 'more than usual' weeks and just having a pity party for myself. take care everyne...