← Return to I'm evidently very treatment resistant, any hope?

Discussion

I'm evidently very treatment resistant, any hope?

Mental Health | Last Active: Sep 29, 2023 | Replies (29)

Comment receiving replies
@johnhans

Robbie I too have had depression all my life and I am 67 now. Unfortunately life is not easy, but I am living proof you can make it through. Actually you may be coming to a better time in your life. If your depression is related to your brain not working to get you feeling good at times, then your brain may work better without the strain of growth and when your brain reaches it's full growth. Your brain develops until age 30 so you still have time to get better. Have you tried therapy? Studies show therapy with antidepressants works the best. Even if you don't have issues that caused the depression, therapy can help you deal with the depression by finding ways to cope with it. I am resistant too. The doctors at Mayo have concluded that if you have tried a number of antidepressants and they do not work, you may need a very large dosage. I take about 4 times the normal dosage. A genetic test can show if some antidepressants do not work with your genes and what they are. Otherwise trial and error works too. If you have tried something at a high dosage and it does not work, then it probably means it will not work for you. Have you tried different doctors? Another doctor may have a different idea of what to do. Be aware that Klonopin can cause depression and tiredness as side effects. I was much better without it. Do not stop any medicine without talking with your doctor and getting his approval.
Please know that I am here with you on this. It is not easy, but it is possible to get through. We are all here with you to let you know we care and are ready to talk with you about your depression. I am praying for you too.

Jump to this post


Replies to "Robbie I too have had depression all my life and I am 67 now. Unfortunately life..."

Thank you for this.
It's just hard when it feels like I've been trying to cope with SOMETHING every single second of every day since...my whole life. I have PTSD (likely c-ptsd) as well, which started from various reasons in my environment from a very very young age (< 3yrs).

The thing with medications is complicated too because they aren't sure whether I have bipolar or not, my episodes are very very unpredictable and don't necessarily always fit into the criteria. Antidepressants cause manic episodes, but I am currently on a mood stabilizer for that and an average dose of Zoloft. I have seen many many therapists and psychiatrists for over a decade. I did do genetic testing a while back, but there were some issues involved and my current psychiatrist wants me to redo it, which I hopefully will soon and get some conclusive results.

@johnhans What a thoughtful and helpful response!! @tricks I too want to encourage you that I agree with what @johnhans says about as getting older you’re likely to have it so severely. I hear you though….I also have tried everything (haven’t tried ect or ketamine ) and feel like nothing is going to work

What’s interesting and I’m 53….is the only two meds that def have helped are clonazepam and adderrall.
I’ve been given grief for years though by family members or random people as well as doctors who say I’m a drug addict for taking those two meds.
I do not abuse or misuse them. I always am trying to titrate down . The adderrall def doesn’t have the same effects as it did for first 5 years or so. But it DOES help more than anything else.

I came to this group to ask about others experience with Ketamine bc I’d really like to try it. Im in MS in a small town so no doctors here yet prescribe it . If anyone has any leads to drs who do that are not too far of a drive please let me know.
I don’t know what Kratom is but not interested in trying it . Have you tried TCMS ??? I did it and it seemed to help a little bit in first few weeks but then made anxiety worse.

Pls don’t lose hope!! Have you ever been for psychological testing ?? I so suggest it if not to get a accurate diagnosis !!