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C. difficile – Are your guts ever normal again?

Digestive Health | Last Active: Jul 15 5:56pm | Replies (646)

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@annapocono

I had cellulitis (hospitalized) in May and then C. Dif in January. Did Vanco and it seemed to work but then got UTI. Finally finally i got into see specialists this week who really knew something bout Diff -- Infectious Disease Specialist and GI with a C.Diff specialty. I have mild MGUS (monoclonal gammopahty of unspecified significant -- which about 3% of people over 65 have) and mild Rheumatoid Arthritis. Both these specialists said that both of those diseases damage a protein that is important to the immune system -- and that they recommended and then the GI offered to do a fecal transplant if I get a relapse which they both thought was pretty inevitable given that my immune system was weak from MGUS and RA. In fact, I may be relapsing now due to antibiotic i took for UTI. In any case, it was the fact that I have these two underlying conditions, which are very common, which seems to have helped me to gain access to FMT. Also I was not told anything about having to pay. I

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Replies to "I had cellulitis (hospitalized) in May and then C. Dif in January. Did Vanco and it..."

For the UTI you should avoid an oral antibiotic and get the shots. Plain old, antibiotic shots like I got when I was a kid. This has been shown to avoid recurrent C. difficile infection because the anabiotic is not going through the intestinal track. As far as FMT goes, please review the warnings on the FDA website about the people who have been killed and whose lives have been greatly compromised as a result of one donor having monkeypox. Three people died right away and two others were very ill. FMT donors are people who are so desperate for money that they sell their poop. These people did not live healthy lives, and their choices are reflected in the quality of their Microbiome. This is a big business. One alternative to FMT is an infusion, called Zinplava. It works like Dificid in that it crippled toxin B and protects you while you immune system recovers. I had recurrent C. difficile in 1993 and almost died. Then, when my husband was terminally ill, they put him in a room where someone had a much more virulent version of C diff and I caught it. I tried everything for more than a year, and then found a doctor at Loyola University, who did not recommend FMT. He pointed out to me that, even though they screen for known pathogens, there are far more unknown pathogens out there. Every bad choice the donor made throughout his life is reflected in his Microbiome. Zinplava was cheaper than FMT and far safer. I recovered and was fine. I had a little IBS for about six months, but it resolved. You aren’t out of the woods because you get FMT. You can never take an antibiotic again for any reason that is orally administered. I took a mild antibiotic for 18 hours for a UTI, and suddenly i had symptoms. I was instructed to stop the antibiotic and take Dificid for one day at 12 hour dosing, then one tab the next day and wait. My body struggled but defeated the CDI. Do some research on the over-the-counter medication‘s that are damaging your micro biome almost as much as an antibiotic, things like antacids, ibuprofen, or other, NSAIDs, anti-depressants just to name a few. Ibuprofen is almost is damaging to the Microbiome as an antibiotic. I had no idea. But I’m glad I found out. I take a wide variety of probiotics, and after the initial bloating, I was greatly relieved and felt much better. I eat a high fiber diet. That is basically Mediterranean. It’s all organic and I never eat any meat, poultry, or eggs that have been treated with antibiotics. The probiotic foods I think are best are kimchi, Kiefer, yogurt, and sauerkraut. The best probiotic I have found is bio K plus extra with wellmune, 80 Billion. I also take two florastor capsules in the morning and two in the evening. And there is a very interesting scholarly article on nih.gov about how chocolate fights cholostridia in the immune system by suppressing it’s replication while at the same time feeding the really good bacteria that keep it in check.