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@kpmirabito

Is there ever a right medication or combination of medications? I’ve been trying different meds for years; at first I feel like I’m better but then I’m right back where I started. I’m going thru a difficult period of totally not caring about anything & of laziness. Which comes first ~ the depression or laziness? I sleep 10 hours a night & 2 hours a day; I just can’t break out of the cycle.

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Replies to "Is there ever a right medication or combination of medications? I’ve been trying different meds for..."

So you have had the same experience with combinatopm of medications! Yes and laziness is also a part of my problem no interest in anything. I do sleep well due to medication but don't sleep in the day. I have tried that and wake up worse feeling. I would try first not to sleep in the day. Even if you just take a short walk in your yard do something other than sleep. Thank you for replying to my email you are appreciated. Patti

@kpmirabito- Welcome to Mayo Connect. This is is an excellent question. I wish I had the answer for it but I wonder about it myself. I was very fortunate not to have any withdrawal symptoms when I weaned off of Effexor. But I had to go on another antidepressant because I'm just wired to have depression. I wish that I knew how much for me it's genetic or behavioral.
Antidepressants can cause apathy and pathos and indolence, etc. This commonly is caused by a number of things. But one can be too much medication. Perhaps you could talk with your doctor about this? What have you done in the past to get out of this?

@jmalibu- Hello. Taking antidepressants and alcohol can exacerbate depression. It can also be very dangerous or change your personality. I always loved drinking martinis- gin martinis. I loved the tradition (my dad use to drink them too), I used to love the whole performance of making them and then the first sip. But after a while my personality started to change and I became a mean person. So I had to stop. I found that I slept better too.
Breaking this cycle, I agree, is extremely difficult. I did it by writing. Then I started a blog about my cancer journey and wrote about it there too.
https://my20yearscancer.com/
What have you done in the past to break out of this?

I don’t think you are lazy at all. One of the symptoms of depression is not sleeping enough or sleeping too much. I think what you are calling laziness is tiredness and lack of energy as a result if the depression. I totally can relate. They are days when I could stay in bed all day. Try to be patient with yourself. It is a very difficult illness to deal with. I’ve found that lying in bed from fatigue that depression can cause is much easier than the irritability resulting from a mixed state that I experience. The irritability is more painful in my
opinion.

Depression is hard. I have depression too. Severe at times. It always a juggling act with meds, side effects. Make sure you have a support group. This helps but you need in person connection too. If there's a NAMI in your area try that. Also have a safety plan. I recommend CBT and DBT therapy groups. Find activities and plan activities once a week with others. I know feeling hopeless is very difficult. I've been there. Some days I had no reason to get out of bed. Maybe keep a depression journal. Take action before you're too depressed. I'm sorry you're going through a hard time. Be kind to yourself.

The depression comes first! There is no way that we would choose to just sit and look all day, every day, at all the tasks waiting for us to take care of. Doesn’t matter what kind of task - I cannot get up and do it. I love love love my bed. We are not lazy! This is depression. I have found that upbeat music helps a lot.