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Neuropathy started during a gout spell
Neuropathy | Last Active: Feb 24 9:08pm | Replies (31)Comment receiving replies
Hello. I just found this discussion, so I apologize if this has been discussed. I had a liver transplant nearly six months ago. It is going well but I suffer from nearly debilitating tremors, muscle pain, numbness in my right leg, occasional nerve pain in my foot and leg, joint pain in knees and hands. Most likely due to Tacrolimus. My liver doctor wants me to see a neurologist for neuropathy. So, I’ve been doing lots of research on it. I’m wondering if others have gone through this as I’m curious as to what to expect and perhaps questions to ask a neurologist. This is so new to me and increasingly worrisome. I do not drink, do not eat refined sugar, no diabetes (yet anyway), and walk and exercise regularly.
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Hello @athenalee, I wasn't familiar with Tacrolimus but did see that some information supporting Tacrolimus induced neuropathy. Excerpt is from the article linked below.
"Peripheral neuropathy is rare but can be a severe side effect of tacrolimus. About 3 of 1000 patients develop severe multifocal demyelinating sensorimotor polyneuropathy 2–10 weeks after initiation of tacrolimus therapy. Dec 5, 2013" - Tacrolimus-induced encephalopathy and polyneuropathy in a renal transplant recipient: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863021/
I think one question I might have - Is there another immunosuppression drug that would work the same or better than Tacrolimus to stop or prevent the neuropathy from getting worse? @rosemarya @gingerw and others may have some suggestions for questions you might want to ask your neurologist based on being a transplant patient.
You are definitely helping your condition by not drinking alcohol, not eating refined sugar and walking and exercising regularly - Kudos to you for that!