Hi. 15- 20 years ago when the peripheral neuropathy first started in both feet, I was om 800 mg. four/d. It helped the pain but was way too much for me. I was in such a stupor that a dozen times while I was trying to eat, my husband would have to wake me because my face would fall into my food. I went down to 600 mg. and eventually 300 two-three times/d.. I still have the tingling all the time and sometimes burning pain or sharp “electric” jolts, but overall, I’m pretty used to it. Primarily, my memory is good, I can make good decisions and take care of myself. Everyone’s height, weight and tolerance is different, so others can tolerate a higher dose.