Hello @profrich. I'd like to invite @dougmann, @james47, @ssid, @eliejose, and @gmack to this discussion as they have all discussed taking imbruvica (ibrutinib) and they may be able to share their experiences with the drug. @profrich, if you don't mind me asking, is this the only side-effect you are experiencing? Has your provider discussed any alternatives with you if this side-effect persists?