Hi @wildcat, thank you for your reply - many aspects of your CMV story sound quite familiar. I am the worried caregiver and my brother is the one recovering from an early April 2020 liver transplant. Like you, the MDs are not sure if the CMV or the valganciclovir (oral - now that he's out of the hospital) and/or one of his other medications are causing some of his symptoms, including breathlessness, diarrhea and fatigue. After about 2 weeks anti-CMV treatment (7 days of IV in the hospital), the virus now is unmeasurable in his blood, but the MDs say it can continue to exist in other compartments in which it is more difficult to detect, such as the gut and, for example, cause diarrhea. Interesting story the MD told us that might be helpful for others: Another liver transplant patient cleared CMV in the blood but continued to have serious diarrhea. Turned out the virus was in her appendix and she improved as soon as they removed it (my brother no longer has his appendix, so not relevant to him). Everyone has such a journey after transplant. It is very helpful to receive the "take heart" message. I do hope we are over the worst!!