Hi - congratulations to your brother! What kind of symptoms is he having? I had side effects from the drugs, notably the high prednisone dose. For awhile I couldn’t finish a sentence, and my husband had to follow me around and turn off the faucet after I washed my hands. It gets better! I’m two months post transplant now and back at work.We always referred back to the ‘transplant bible’ to see if symptoms were a sign of rejection. If not and it didn’t seem serious I reviewed it with the doctor during my clinic visits. I wouldn’t be afraid to contact the transplant coordinators. They’ve been through just about everything with other patients and are a wealth of information. If nothing else, they can put your mind at ease.