@musicman2019 I don't have any of the listed side effects of TACROLIMUS. My labs confirmed I have extremely low T that will be treated by hormone shots this month. I read it is common with male transplant recipients.

@musicman2019 I was on tacrolimus after transplant and my creatinine started climbing. I was told to drink 80 - 100 ounces of fluid a day but that did not help much so they switched me to sirolimus. I still drink all of that water but I no longer have a creatinine problem. They really keep track of me, very thoroughly.
I also started having bad diarrhea while on tacrolimus. I was hoping with the change to sirolimus that would go away but it did not. I have come to realize that I now am lactose intolerant. I believe the tacrolimus must have triggered that since it happened right after starting tacrolimus.
JK

@musicman2019, Welcome to Connect. I am a transplant recipient, and I have been taking tactolimus since my simultaneous liver and kidney transplant in 2009. I have needed only minor adjustments to my dosage in the early years. I have been on my current dosage for the past 4 years. My labs are drawn at 3 month intervals, and it includes a test that provides information about the level of the prograf/tacrolimus in my blood. There is a therapeutic range that my transplant teams have assigned to me. It is necessary for the level to be high enough to suppress the immune system, and also low enough to be least harm to the body.

Here is a list of side effects for tacrolimus.
https://www.mayoclinic.org/drugs-supplements/tacrolimus-oral-route/side-effects/drg-20068314
musicman2019, Are you currently taking tacrolimus? Do you have a transplant, or are you considering a transplant?