All my ANA tests were positive. They would see the butterfly rash and order tests, then tell me positive. One Dr was very rude. So googled it and about 15 yrs ago found a lesser known test called anti-sm also called anti-smith, only shows up in lupus. I tested positive 3 times, Dr said don't worry it's not active. Then last several yrs tested neg, was told those numbers go up and down. Had friend who almost died a few times, spent off and on in hospital for 1 yr, every doctor gave a completely different disease, everyone different! After a yr he checked out of hospital went home, we don't know if he's in pain or not, but I found what it was also last Dr said same thing, friend said no more tests.