thanks, that would be great. very interested to hear the response. and you're right -- like you, i suspected that my doctor would have disapproved if i asked her first. how could she approve, after all? almost no doctor is going to say yes if you ask them point-blank if you can alter the dosage of your drug in a non-evidenced based way. now, in retrospect, however, my very small experiment of n = 1 🙂 seems at least to suggest that small body size + exaggerated side effects may indicate that a reduced dosage of tymlos can be effective. if for some reason, i had been unable to try a reduced dosage, i would have just stopped the drug.