hi all: i had contributed to this thread in the past, and i thought i would update you. i began tymlos almost a year ago after having done prolia injections for three years. in other words, i had 6 twice-yearly injections of prolia (with improvements in bone density), and at that point, my doctor advised a switch to another medication due to the brittle bone potential that prolia can pose with prolonged use. i had had no side effects with prolia, but with tymlos, i had pretty much all of them. i had the racing heart, headache, and nausea with each and every injection. last week, my dexa scan showed that the bone density in my spine had increased by 14.4% over the ten-month period -- i actually crossed back over the line into osteopenia again. it's a relief. i watched my grandmother spend the last years of her life permanently doubled over as her vertebrae collapsed. sending best wishes to everyone with their treatment.