Hello @tllaes

On a personal note, while I've never tried Rytary, I have known members from a PD support group that I attend who did try it when it first came out and gave it rave reviews, but that is not a personal recommendation of course, only the evaluations of others.

I suppose you have already tried the long-lasting Sinemet? It goes by the name of Stalevo (the generic name is Carbidopa/Levodopa/Entac). It is the Entac (Entacapone) that makes the other ingredients last longer. You can also take the Entacapone as a single drug. I find that one Stalevo per day works quite well for me along with 2 Sinemets.

I have a friend from a PD support group, here in SE Michigan, who recently was in a clinical trial with a pump. It is a pump on the outside of the body and it gives her a steady stream of med. It has worked quite well for her, but as it was part of a clinical trial and I don't know if it will go on the market or not. You might do some research on it and see what you can find or ask your neurologist to check into it.

I hope that you are able to find a solution for your PD symptoms soon. Will you update me on how you are doing?

Teresa