Barbara - Correct. I asked my P.A. the last visit if I could go on Venetoclax (due to promising trials of taking both Venetoclax and Imbruvica or only Venetoclax) but was told they want to keep that or other next step drugs in reserve for when/if the imbruvica fails. I was thinking that if it could get myself to minimal residual disease that it would be good to blast the cancer now with all they got, but the dr and the specialist both were talking about plan A, plan B etc.and to keep treatment next steps in reserve. So for me, Venetoclax would be what I would ask for next since I have the 17p deletion. I don't want to have the stem cell transplant. For me I'll do anything before that - it's too scary to have bone marrow killed and then someone else's put in, Seems that the average is 60% success rate, so I'd have to save that as the last option The leukemia and lymphoma society page for B-PLL still says "While ibrutinib and idelalisib have not currently been FDA approved to treat B-PLL, they have been approved to treat other B-cell malignancies." But I'm already on Imbruvica now for a year and 4 months. They need to update pages and we need to push for drugs since we're not numerous enough to have our own clinical trials for B-PLL. In some clinical trials it seems we are allowed in with other conditions like CLL/SLL (I go to clincialtrials dot gov ). I already know that I'd not consider a clinical trial using fludarabine plus other drugs (it didn't work at all for me when dr's tried it on me)

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