Dearest Ann, You seem to be going through a lot more than I have so far. Yes, the expensive drug was imbruvica-stopped after a bone marrow test which confirmed the B-PLL.The hardest part seems to be not being diagnosed until changing Primary doctors. Eccept for needing infusions closer each time,there was no sign of the cancer until the interveinous chemo made it worse. At one time I had given up,but I am only 87and intend to enjoy what time I have left.