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Completed 5 years of anastrozole. Withdrawal symptoms? Side effects?
Breast Cancer | Last Active: Nov 2 9:07am | Replies (291)Comment receiving replies
Hello , My mother had Stage 3b metastatic breast cancer 4 years ago . Had 8 rounds of chemo and 33 radiations , right after she was put on anastrozole she is 66 years old , she wanted to get off of it , she said her bones hurt all the time and her "chemo brain" was bad after 3 years . So it has been 2 months and for 2 months my mother has been in a Delirium state of mind . she got a catscan and blood work done and everything came back good . doctor says it wouldnt be from stopping the medication but I dont believe that ... they are saying she has dementia now ..... anyone else have anything like this happen ?
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@edini1712
Anastrozole did indeed do a number of adverse things to my skin, hair, bones, and joints, etc., but from what I read, my memory issues were likely an effect of the chemotherapy (Taxol in my case) at my age. One bright note came a year ago with a report in which researchers suggested that women who used hormone-modulating breast cancer treatments (SERMs like tamoxifen and aromatase inhibitors like anastrozole) were less likely to be diagnosed with neurodegenerative disease. They followed almost 58,000 women for over 5 years which makes it a significant study. Here's the subject article:
https://oncology.medicinematters.com/breast-cancer/dementia/breast-cancer-treatments-may-ward-off-alzheimers-disease/17854966
Is that conclusive? No, it's just a very large study. I am sorry for what your mom is going through, and I can only hope that her doctors soon find a resolution to her situation.