I have stopped taking Anastrozole after just over 5 years' treatment. Most important for medical personnel and researchers and manufacturers is that my reaction which has included fatigue and energy/ mood swings dramatically entered a massive suicidal depression approx 9 days after stopping. I have only once experienced suicidal thoughts in my life and that was following a major relationship break up. I was weepy and feeling very unworthy and alone. I also wanted to self-harm. Again I have no history of this ideation. My GP knew nothing of these possible results - and in fact anticipated I would feel better for being off the tablets. So I believe it is very important to share this information far and wide. Fortunately I was able to find some resources within my which steered me off these destructive urges and had friends to de-brief with in the following days. This is now 4 weeks since stopping and mood and energy swings continue but not the major depression.