You sound like a candidate for Genesight testing. Information at info@assurexhealth.com. It's a gene test that tells you what drugs will work for you. Depression, anxiety drugs, stimulants, ie Wellbutrin etal. Also what pain drugs will work based on your genes. You ask them for a list of docs close to you who preform this service and go to one who does, they take a cheek swab and in about 2 weeks you have your results back. It alerts you to drug interactions you could have as well as what drugs in 3 or 4 classes will work for you based on how you metabolize them. It's new and it's nothing short of a miracle for folks who need meds like Cymbalta and Wellbutrin. Quit guessing because that's all you and your doc are doing and find out what will work for you. That website is info@assurexhealth.com. get there number and call them and ask them to email you a list of docs near you. Doctors can register for free and all it takes for them is a fifteen minute phone call. If your doc doesn't do it see one who does. Get your info and take it back to the doctor you have and like. When they see the info, they will come around. Good luck, do it!!!