Hi, I think conventional wisdom is to titrate off one med at a time and allow your brain and body to stabilize before moving onto other titrations. Usually withdrawal symptoms like anxiety, etc. become unmanageable if the titration is too fast, and too high. If you've found a titration dose that is manageable, then stay "there" awhile. It's even o.k. to back up a little to a smaller, higher dose, stabilize, and then proceed on with very small, incremental titrations. When I started titrating various meds - I just wanted off all of them as fast as possible and that was a mistake. Here is a link with a lot of information about titration. The "brassmonkey" method is a little involved for me right now. (I'm still a little muddled from lack of sleep.) but the general rules are excellent. https://www.survivingantidepressants.org/topic/17671-the-brassmonkey-slide-method-of-micro-tapering/?tab=comments#comment-347786 - best of luck hang in there - it does get better. I slept last night - yay - I took 25 mg of organic, high-absorbancy magnesium, drank 2 cups of Sleepytime herbal tea, and took my .25 mg (1/2 of .5) of lorazepam. (I've already titrated off lamotrigine, lexapro, seroquel and am now down to .25 lorazepam and less than 5 mg trintellix.) I'm currently looking into using tart cherry concentrate as a natural "melatonin." Will post with the results if they prove encouraging.