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← Return to Getting off of Seroquel
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Depression & Anxiety | Last Active: 1 day ago | Replies (730)
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Hello, @ellensf - welcome to Mayo Clinic Connect. That is very difficult to have severe symptoms with tapering down on your quetiapine (Seroquel) with some anxiety, difficulty talking on the phone and brain fog.
Here is some Mayo Clinic information on the medication you mentioned https://www.mayoclinic.org/drugs-supplements/quetiapine-oral-route/description/drg-20066912. The Precautions section might be particularly helpful https://www.mayoclinic.org/drugs-supplements/quetiapine-oral-route/side-effects/drg-20066912?p=1
Are you feeling that your use of the quetiapine (Seroquel) is related to the memory problems you describe, or is this a separate issue?
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Although I have been on Seroquel 400 XR for many years, my memory started to get really bad over the last 2 years. I don't think Seroquel caused this level of memory loss, but there is a good chance it is contributing to it. Normally I need 8 - 9 hours of sleep. After going down on Seroquel by 25mg for 4 days I needed 12+ hours of sleep. When I wake up I take 400 mg of Provigil and am ok for several hours. 2 days ago I only got 9 hours of sleep and 400 mg of Provigil did nothing. Last night I got less sleep and am not tired, but I have Bipolar Disorder and i get a very mild type of hypomania where I don't get enough sleep and am not tired for several days in a row. Over the next week I'll see if reducing by 25 is still causing such severe sedation.