My son has been on and off of Quetiapine/Seroquel for years. Most recently his dose has been 100 mg at night for about a year. Experienced extreme lethargy and no motivation along with tremors. So decided to go off of it. Doctor suggested reducing to 50 mg for a week then 25 mg for a week and stop which he has done. Now off of it for 3 days. He has been vomiting for those 3 days. Can't keep anything down and hasn't eaten. Has been taking anti-nausea meds and ok for a while but then still throws up. I'm just wanting to know how long these symptoms will be lasting. Not sure if he tapered too quickly? Called Doctor and he said he could go back on it and take 12.5 mg every night for a week and then do 12.5 mg every other night for another week and then stop it. I'm not sure if its better to do that or if it will just prolong him getting off of it. Maybe he should just try to deal with the withdrawal for another few days rather than go back on the meds? Has anyone ever tapered from 100 mg in a 2 week period? And if so what was your experience? This is not an easy process. Didn't realize it would be this bad.