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Getting off of Seroquel

Depression & Anxiety | Last Active: Nov 16 4:15pm | Replies (724)

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@mrsminniemouse

Hi there
My 16 year old daughter has been taking 25mg of quetiapine plus 40 mg fluoxetine for a couple of years. She is much improved and I don’t feel she needs the anti-psychotic now. Two nights ago, she forgot to take her meds and was like a different person the next day. More engaged and vibrant. I think the quetiapine was necessary when she was suicidal a couple of years ago but not now. I fear it is dulling her true feelings.
If we were to reduce her quetiapine would we cut the daily 25mg tablet in half or go to 25mg on alternate days? I will try to contact her psychiatrist but she’s moved away and a replacement was never given.
Any advice or shared experience much appreciated. Thank you 😊

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Replies to "Hi there My 16 year old daughter has been taking 25mg of quetiapine plus 40 mg..."

Hello, @mrsminniemouse. Welcome to Mayo Clinic Connect. You may notice I moved your discussion and combined it with another discussion titled, "Getting off Seroquel." I did this so many members on Connect discussing this topic would see your message and have a chance to add their thoughts.

You sound like a caring mom who is looking out for her daughter. That makes things more complicated with looking to have your daughter taper down the quetiapine (Seroquel) with no assigned psychiatrist to advise when your former physician moved away.

I have not taken quetiapine (Seroquel) personally, but years ago when I was on citalopram (Celexa), I eventually noted what you are talking about - dulling of my feelings. I noticed I was not experiencing low lows anymore, but it was like I was incapable of experiencing high highs anymore, either. My psychiatrist explained that this was legitimate - that some psych meds do just that.

I'm sure some of the members here will have some tips from their experiences tapering off this medication. What you are doing by contacting the psychiatrist or requesting another to supervise and guide the taper is a good move.

Are you looking to talk to the psychiatrist (whomever is consulting) about switching to another medication instead, or going off of this class of medication altogether, @mrsminniemouse?