Hi, @num1boxer1919 - welcome to Mayo Clinic Connect. I can imagine you would be very uncomfortable with the heart racing from the quetiapine (Seroquel), and it's understandable you are looking for an alternative.

If you click on VIEW & REPLY in your email notification, you will see the whole discussion and can join in, meet, and participate with other members talking about their experiences.

I'd invite @flpatt @anniegk @yangedd @highserotonin30 @mxyzptlk @tness360 to return and speak to their experiences with quetiapine (Seroquel) and any heart racing they may have encountered, and share any thoughts they may have on alternatives for antipsychotics or insomnia.

I'd also suggest looking at this thread on insomnia in our Sleep Health group, which may have lots of ideas for you and would be a great place to interact with others who are trying to get better sleep https://connect.mayoclinic.org/discussion/josephene-i-am-having-terrible-insomnia-as-well-nothing-seems-to-help.

Have you had the chance to ask the prescribing doctor for the quetiapine (Seroquel) for an alternative, or some means to deal with the heart-racing side effect, @num1boxer1919? Are you getting much sleep right now?

@num1boxer1919
Hey buddy,
Klonopin is the most difficult medication I ever discontinued. Although I don’t have a clear memory of that time I did not have serious withdrawal issues which I attribute to how slowly I stopped. I don’t remember any sleep issues back then. You should never increase your dose without notifying your doctor.
Are you taking any other prescription medications currently? If so, what are they and what dosage? These medications and
alcohol don’t mix. Whether or not it’s withdrawal or illness that’s something only a doctor or psychologist is qualified to diagnose. However I would question why your doctor prescribed such a powerful drug for a sleep issue. It can actually interfere with the sleep cycle. You may want to ask about that as well. Seroquil is a dangerous Antipsychotic. Seroquil is intended for treating people with Schizophrenia. Many researchers believe as I always have that this drug should not be used for off label purposes. Prior to me being appointed his conservator he was given a Neuroleptic and now is suffering from an irreversible moment disorder. Unless you are suffering from a severe mental illness forget about Neuroleptics. There are many safer treatments for sleep issues.
Okay moving on. I recently ran across a table that shows the difference and the inconsistency of the titration percentages per month vs by dose. But I’m unable to locate it now. I’ll put it up if I can find it.

My theory of titration and that of many researchers is a 5-10% decrease, per dose. A lot of this information comes from the people who have tried various titrations and most are finding this the most effective. It is very important however that the 5-10% is based on each titration dose and not a particular percentage per 2 weeks or month. The problem with 5-10% per month is that although in the beginning your dose decrease is indeed 5-10%, but the farther into your titration you get those percentages start to jump all over the place, some decreases are 33% some lower some as high as 50%. The problem being the titrations are not consistent. Admittedly it’s going to take more time but the chance of withdrawal is almost non existent. There is a member here who is decreasing their dose by less than one half of 1 percent each month. Even at that rate, they are having symptoms.
I wish you the best, you can do it,
Jake