For me, sublingual CBD is an adjunctive medication with Tramadol and Lyrica for severe Neuropathy/plantar fasciitis and arthritis. For intense burning of feet, ankles and lower leg, I find that CBD ointment, like Mitchell's or Lazarus, acts quickly and effectively--does not help with deeper pain. I also find that the sublingual CBD has a mild calming effect that helps me handle the pain. My doctors agree that I should replace CBD with medical marijuana, but I tried it a few times about 50 years ago and found I liked it too much. I do not have problems following instructions with any pain meds, but fear that I might with MJ. I have tried stronger pain medications for short periods. I am sticking with Tramadol, because I want to be clear headed. Do your homework on brands, quality, types. CBD is very expensive, but often has discount coupons. Personally, I found that a large, well known and high quality CBD manufacturer that heavily discount for veterans and disabled or senior citizens--Lazarus brand.