Yes, I have been using it for about 4 months. It does seem to give me some relief. The attacks I get in the evening don't seem as intense. I take it orally a squirt under the tongue in the morning and at night. Perhaps the topical is better I just have not tried that.....Here in St Louis MO. The Post Dispatch paper had adds for stem cell treatments for various problems and one day they ran the add for peripheral neuropathy. I showed it to my doctor and he was going to consult another doctor that might be familiar with that area but so far I have not heard back. Does anyone know about this ? Thanks Jerry