@sukrutp- Welcome to Mayo Clinic Connect. It looks as if you have done a lot of things to change your life to help the SOB, especially losing weight. I encourage you to read the posts in this discussion as others like you have basically the same symptoms. I wouldn't rule out GERD as the reason for your SOB. Finding out the cause for it can be tricky and GERD can be difficult to diagnose because it's sometimes unreliable in the way that it acts.