@tonyagregg did you ever get any answers?? I feel like you just told my entire story...even down to the fact that I have Gilbert’s (Diagnosed in 2007)...I feel less crazy knowing I’m not the only person who’s experienced this. My SOB started in 2016 and is intermittent and exactly like you described. I can’t find answers. I, too, have taken Prilosec. I can’t find much of a pattern. It’s just uncomfortable and strange to be so vague and mysterious. When I read your post I felt like you were describing exactly what I’ve gone through. Any other help that you’ve received since your post? Thanks!