I have bad anxiety and depression when i first get up and sometimes late at night as well. Do you mind if i ask what medication you are on? Iam on mirtazapine, seroquel, and buspar. I dont think they are working for me. Iam going to the doctor tomorrow and will talk to them. I have been titrating off of the seroquel. I was on 300 mgs and now Iam on 200. I have been on it for over a year and the doctor said i could go down to 200. I want to be completely off of it. I dont like the way it makes me feel.